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KMID : 0380020100250020173
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Korean Journal of Biotechnology and Bioengineering
2010 Volume.25 No. 2 p.173 ~ p.178
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Antifungal Effect of Bilobalide and Ginkgolide Extracted from Leaves of Ginkgo biloba Against Pityrosporum ovale
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Lee In-Hwa
Kim Mi-Jin
Choi Jun-Ho
Choi Seung-Hyun
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Abstract
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Antifungal effect of Ginkgo biloba leaves extracts conducted for Pityrosporum ovale. Antifungal effect verified by diffusion test, optical density test and colony counting test under various concentration. Extract of ginkgo biloba leaves performed with 40% ethanol and 60% water solution at 60℃ and major components analyzed by HPLC. The concentrated extract have bilobalide and ginkgolide A and ginkgolide B and their concentration were 153.0 mg/L, 8403.5 mg/L and 2723.0 mg/L respectively. Ginkgo biloba leaves extracts gave 99.1% of antifungal effect for Pityrosporum ovale examined by colony counting method.
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KEYWORD
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Ginkgo biloba leaves extract, Pityrosporum ovale, bilobalide and ginkgolide, antifungal effect
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